Voriconazole for the treatment of refractory Aspergillus fumigatus keratitis.
Identifieur interne : 004A03 ( Main/Exploration ); précédent : 004A02; suivant : 004A04Voriconazole for the treatment of refractory Aspergillus fumigatus keratitis.
Auteurs : Hijab Mehta [Inde] ; Hitendra B. Mehta ; Prashant Garg ; Harish KodialSource :
- Indian journal of ophthalmology [ 0301-4738 ]
English descriptors
- KwdEn :
- Antifungal Agents (therapeutic use), Aspergillosis (drug therapy), Aspergillosis (microbiology), Aspergillus fumigatus (isolation & purification), Corneal Ulcer (drug therapy), Corneal Ulcer (microbiology), Eye Infections, Fungal (drug therapy), Eye Infections, Fungal (microbiology), Female, Humans, Middle Aged, Pyrimidines (therapeutic use), Triazoles (therapeutic use), Voriconazole.
- MESH :
- chemical , therapeutic use : Antifungal Agents, Pyrimidines, Triazoles.
- drug therapy : Aspergillosis, Corneal Ulcer, Eye Infections, Fungal.
- isolation & purification : Aspergillus fumigatus.
- microbiology : Aspergillosis, Corneal Ulcer, Eye Infections, Fungal.
- Female, Humans, Middle Aged, Voriconazole.
Abstract
We report a case of Aspergillus fumigatus keratitis in a 53-year-old, well-controlled diabetic female who did not respond to standard antifungal treatment. She was started on topical natamycin eye drops, but the infiltrate continued to progress. Topical amphotericin B and systemic ketoconazole was added, however, there was no response and the infiltrate increased further. She was then switched to topical and systemic voriconazole. Steady resolution of the infiltrate was noted within 2 weeks of therapy.
PubMed: 18417831
Affiliations:
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Le document en format XML
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Mehta</name></author><author><name sortKey="Garg, Prashant" sort="Garg, Prashant" uniqKey="Garg P" first="Prashant" last="Garg">Prashant Garg</name></author><author><name sortKey="Kodial, Harish" sort="Kodial, Harish" uniqKey="Kodial H" first="Harish" last="Kodial">Harish Kodial</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="????"><PubDate><MedlineDate>2008 May-Jun</MedlineDate></PubDate></date><idno type="RBID">pubmed:18417831</idno><idno type="pmid">18417831</idno><idno type="wicri:Area/PubMed/Corpus">000431</idno><idno type="wicri:Area/PubMed/Curation">000431</idno><idno type="wicri:Area/PubMed/Checkpoint">000828</idno><idno type="wicri:Area/Ncbi/Merge">000488</idno><idno type="wicri:Area/Ncbi/Curation">000488</idno><idno type="wicri:Area/Ncbi/Checkpoint">000488</idno><idno type="wicri:doubleKey">0301-4738::Mehta H:voriconazole:for:the</idno><idno type="wicri:Area/Main/Merge">004B79</idno><idno type="wicri:Area/Main/Curation">004A03</idno><idno type="wicri:Area/Main/Exploration">004A03</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Voriconazole for the treatment of refractory Aspergillus fumigatus keratitis.</title><author><name sortKey="Mehta, Hijab" sort="Mehta, Hijab" uniqKey="Mehta H" first="Hijab" last="Mehta">Hijab Mehta</name><affiliation wicri:level="1"><nlm:affiliation>Infiniti Eye Hospital, Jaya Mahal, French Bridge, Opera House, Mumbai-400 007, Maharashtra, India. drhijabmehta@gmail.com</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>Infiniti Eye Hospital, Jaya Mahal, French Bridge, Opera House, Mumbai-400 007, Maharashtra</wicri:regionArea><wicri:noRegion>Maharashtra</wicri:noRegion></affiliation></author><author><name sortKey="Mehta, Hitendra B" sort="Mehta, Hitendra B" uniqKey="Mehta H" first="Hitendra B" last="Mehta">Hitendra B. Mehta</name></author><author><name sortKey="Garg, Prashant" sort="Garg, Prashant" uniqKey="Garg P" first="Prashant" last="Garg">Prashant Garg</name></author><author><name sortKey="Kodial, Harish" sort="Kodial, Harish" uniqKey="Kodial H" first="Harish" last="Kodial">Harish Kodial</name></author></analytic><series><title level="j">Indian journal of ophthalmology</title><idno type="ISSN">0301-4738</idno></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Antifungal Agents (therapeutic use)</term><term>Aspergillosis (drug therapy)</term><term>Aspergillosis (microbiology)</term><term>Aspergillus fumigatus (isolation & purification)</term><term>Corneal Ulcer (drug therapy)</term><term>Corneal Ulcer (microbiology)</term><term>Eye Infections, Fungal (drug therapy)</term><term>Eye Infections, Fungal (microbiology)</term><term>Female</term><term>Humans</term><term>Middle Aged</term><term>Pyrimidines (therapeutic use)</term><term>Triazoles (therapeutic use)</term><term>Voriconazole</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Antifungal Agents</term><term>Pyrimidines</term><term>Triazoles</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Aspergillosis</term><term>Corneal Ulcer</term><term>Eye Infections, Fungal</term></keywords><keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>Aspergillus fumigatus</term></keywords><keywords scheme="MESH" qualifier="microbiology" xml:lang="en"><term>Aspergillosis</term><term>Corneal Ulcer</term><term>Eye Infections, Fungal</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Female</term><term>Humans</term><term>Middle Aged</term><term>Voriconazole</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">We report a case of Aspergillus fumigatus keratitis in a 53-year-old, well-controlled diabetic female who did not respond to standard antifungal treatment. She was started on topical natamycin eye drops, but the infiltrate continued to progress. Topical amphotericin B and systemic ketoconazole was added, however, there was no response and the infiltrate increased further. She was then switched to topical and systemic voriconazole. Steady resolution of the infiltrate was noted within 2 weeks of therapy.</div></front></TEI><affiliations><list><country><li>Inde</li></country></list><tree><noCountry><name sortKey="Garg, Prashant" sort="Garg, Prashant" uniqKey="Garg P" first="Prashant" last="Garg">Prashant Garg</name><name sortKey="Kodial, Harish" sort="Kodial, Harish" uniqKey="Kodial H" first="Harish" last="Kodial">Harish Kodial</name><name sortKey="Mehta, Hitendra B" sort="Mehta, Hitendra B" uniqKey="Mehta H" first="Hitendra B" last="Mehta">Hitendra B. Mehta</name></noCountry><country name="Inde"><noRegion><name sortKey="Mehta, Hijab" sort="Mehta, Hijab" uniqKey="Mehta H" first="Hijab" last="Mehta">Hijab Mehta</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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